Satiety and glycemic control after giving glucomannan-modified growol cookies

Desty Ervira Puspaningtyas; Adi Sucipto; Silvia Dewi Styaningrum; Puspita Mardika Sari; Anita Nidyarini; Dwita Mukti Rahmawati; Getha Puji Lestari; Renata Deby Sintia; Dhea Putri Ananda

doi:10.21927/ijnd.2024.12(4).284-295

Satiety and glycemic control after giving glucomannan-modified growol cookies

Desty Ervira Puspaningtyas, Adi Sucipto, Silvia Dewi Styaningrum, Puspita Mardika Sari, Anita Nidyarini, Dwita Mukti Rahmawati, Getha Puji Lestari, Renata Deby Sintia, Dhea Putri Ananda

Abstract

Background: Obesity has become an epidemic in all parts of the world. One in five deaths is related to obesity predisposition. Providing foods high in fiber can be a solution to treating obesity. The addition of glucomannan to growol cookies can optimize the fiber content of food which will have an effect in controlling satiety and glycemic control.

Objective: To study the effect of glucomannan-modified growol cookies, as a healthy snack in the context of preventing obesity, on changes in satiety and blood glucose levels in excessive-weight subjects (ES) and normal-weight subjects (NS).

Methods: A quasi-experimental study with a pre-post design without a control group was conducted on 30 subjects (15 NS and 15 ES). The research was carried out at Universitas Respati Yogyakarta in June-July 2023. The satiety test was carried out using the SLIM (Satiety Labeled Intensity Magnitude) method. Blood glucose levels were measured using the Rapid Test method using Easy Touch GCU before, immediately after, and 120 minutes after giving cookies. Data on satiety and blood glucose levels were sequentially analyzed using the Wilcoxon Signed Ranks Test and Paired Samples T Test (comparing before and after intervention) as well as the Mann-Whitney U Test and Independent Samples T Test (comparing between groups) with a significance of 95%.

Results: There was a difference in the feeling of fullness between the 0th minute, 30th minute, 60th minute, and 90th minute compared to the initial feeling of fullness (basal) in the entire group (p<0.05). There was no difference in blood glucose levels between fasting blood glucose, 0-minute blood glucose, and 120-minute blood glucose. Glucomannan-modified growol cookies can delay hunger for 1-1.5 hours before the next big meal. Glucomannan-modified growol cookies can also maintain blood glucose stability in the range of 90 mg/dL.

Conclusion: Glucomannan-modified growol cookies can have a positive effect on satiety control and glycemic control.

Keywords

glucomannan; glycemic control; growol cookies; obesity; satiety

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References

World Health Organization Regional Office for Europe. Nutrition, overweight and obesity [Internet]. Factsheet - Sustainable Development Goals: health targets. 2021. Available from: https://apps.who.int/iris/bitstream/handle/10665/341982/WHO-EURO-2021-2574-42330-58595-eng.pdf

UNICEF. Landscape analysis of overweight and obesity in Indonesia. Jakarta: United Nations Children’s Fund; 2022. 45 p.

Kurniawaty E, Syukur S, Yanwirasti, EtiYerizel. Correlation between obesity and type 2 diabetes mellitus using PPARγ2 gene varian. Biochemical and Cellular Archives. 2019;19(Supplement 2):4807–9.

Fajarini IA, Sartika RAD. Obesity as a common type-2 diabetes comorbidity: Eating behaviors and other determinants in Jakarta, Indonesia. Kesmas: National Public Health Journal. 2019;13(4):157–63.

Wondmkun YT. Obesity, insulin resistance, and type 2 diabetes: Associations and therapeutic implications. Diabetes, Metab Syndr Obes Targets Ther. 2020;13:3611–6.

Y. Parmar M. Obesity and type 2 diabetes mellitus. Integritas Obesitas Diabetes. 2018;4(4):1–2.

Kosupa DZ, Utama F. Relationship between obesity and diabetes mellitus in people above 40 years old in Indonesia: A retrospective cohort study, analysis of 2007 and 2014 Indonesian Family Life Survey Data. 2020;25(Sicph 2019):228–34.

Abbas A. Meta analysis of the relationship of obesity with type 2 diabetes mellitus in Indonesia. Jurnal Ilmu Kesehatan [Internet]. 2021;10(1):276–82. Available from: https://sjik.org/index.php/sjik/article/view/621/451

Sumadewi KT, Karmaya NM, Adiatmika IPG. Korelasi antara kadar leptin dengan IMT, lingkar pinggang dan RLPP pada orang dewasa obesitas usia 19-25 tahun di Universitas Warmadewa. WMJ (Warmadewa Med Journal). 2016;1(2):71–82.

Purnell JQ. Definitions, classification, and epidemiology of obesity - Endotext - NCBI Bookshelf. 2018. p. 22–8.

US Department of Health and Human Services. National diabetes statistics report, 2020. National Diabetes Statistics Report. 2020.

Puspaningtyas DE, Sari PM, Kusuma NH, Helsius SB D. Analisis potensi prebiotik growol: kajian berdasarkan perubahan karbohidrat pangan. Gizi Indonesia. 2019;42(2):83–90.

Helsius SB D, Inayah I, Puspaningtyas DE, Sari PM, Kusuma NH. Effect of cassava fermentation on reducing sugar and sucrose levels: a preliminary study of healthy snack development. Journal Healthc Biomedice Science. 2023;1(2):20–34.

Helsius SB D, Inayah I, Puspaningtyas DE, Sari PM, Kusuma NH. Diversity of traditional fermented foods: sucrose and reducing sugar analysis of various fermented-cassava. Medical and Health Science - Proceeding RSF Press 2023;2(1):27–35.

Puspaningtyas DE, Sari PM, Kusuma NH, Helsius SB D. Indeks glikemik cookies growol: studi pengembangan produk makanan selingan bagi penyandang diabetes mellitus. Jurnal Gizi Klinik Indonesia. 2020;17(1):34–42.

Puspaningtyas DE, Nekada CDY, Sari PM. Penambahan inulin terhadap indeks glikemik dan beban glikemik cookies growol: pengembangan makanan selingan diabetes. AcTion: Aceh Nutrition Journal. 2022;7(2):169.

Styaningrum SD, Sari PM, Puspaningtyas DE, Nidyarini A, Anita TF. Analisis warna, tekstur, organoleptik serta kesukaan pada kukis growol dengan variasi penambahan inulin. Ilmu Gizi Indonesia. 2023;06(02):115–24.

Yanuriati A, Marseno DW, Rochmadi, Harmayani E. Characteristics of glucomannan isolated from fresh tuber of Porang (Amorphophallus muelleri Blume). Carbohydr Polym [Internet]. 2017;156:56–63. Available from: http://dx.doi.org/10.1016/j.carbpol.2016.08.080

Rachmaniah O, Juliastuti SR, Wisnu MM, Samparia DA, Hendrianie N, Darmawan R, et al. Purified konjac glucomannan as thickener for substituting gelatin in making panna cotta. Halal Research Journal. 2024;4(1):28–38.

Mohammadpour S, Reza M, Shahinfar H, Jibril A, Shahavandi M, Ghorbaninejad P, et al. Effects of glucomannan supplementation on weight loss in overweight and obese adults : A systematic review and meta-analysis of randomized controlled trials. Obesity Medicine. 2020;19(44):1–7.

Maia-Landim A, Ramírez JM, Lancho C, Poblador MS, Lancho JL. Long-term effects of Garcinia cambogia/Glucomannan on weight loss in people with obesity, PLIN4, FTO and Trp64Arg polymorphisms. BMC Complement Altern Medicine. 2018;18(1):1–9.

Mashudi S, Susilo HM, Putri DR, Saifullah S T, Hariyatmi. Konjac glucomannan reduce blood sugar levels in obesity adolescents. In: 1st International Conference on Innovation in Science, Education, Health and Technology. 2022. p. 189–93.

Nissa C, Madjid IJ. Potensi glukomanan pada tepung porang sebagai agen anti-obesitas pada tikus dengan induksi diet tinggi lemak. Jurnal Gizi Klinik Indonesia. 2016;13(1):1–6.

Zalewski BM, Szajewska H. Effect of glucomannan supplementation on body weight in overweight and obese children: Protocol of a randomised controlled trial. BMJ Open. 2015;5(4):1–5.

Fathimah FZ, Mulyati T. Pengaruh pemberian sarapan tinggi protein terhadap tingkat rasa kenyang wanita obesitas. Journal of Nutrition College. 2015;4(1):10–7.

Susanti N, Nissa C, Serina SN, Ratnawati R, Nurdiana, Sumitro SB, et al. Supplementation of glucomanan derived from konjac flour improve glucose homeostasis and reduce insulin resistance in diabetes rat models. Pakistan Journal Nutrition. 2015;14(12):913–8.

Orra AA El, Pires MM, Ferreira SRG. Distinct breakfast patterns on satiety perception in individuals with weight excess. Arch Endocrinol Metab. 2016;60(4):333–40.

Iqbal M, Puspaningtyas DE. Penilaian Status Gizi ABCD. 1st ed. Sulia A, Utami T, editors. Jakarta: Salemba Medika; 2018.

Sari PM, Puspaningtyas DE, Styaningrum SD, Sucipto A, Ananda DP, Sintia RD. Pengaruh penambahan glukomanan dari umbi porang terhadap kandungan gizi cookies growol sebagai pangan fungsional untuk obesitas. SAGO Gizi dan Kesehatan. 2024;5(2):446–55.

Potter M, Vlassopoulos A, Lehmann U. Snacking recommendations worldwide: A scoping review. Advances in Nutrition. 2018;9(2):86–98.

Behera SS, Ray RC. Konjac glucomannan, a promising polysaccharide of Amorphophallus konjac K. Koch in health care. International Journal of Biological Macromolecules [Internet]. 2016;92(May):942–56. Available from: http://dx.doi.org/10.1016/j.ijbiomac.2016.07.098

Saroh SM, Mundiastuti L. Daya terima dan uji kekenyangan pada bakso yang disubtitusi jantung pisang dan modified cassava flour (Mocaf). Amerta Nutrition. 2018;2(2):155–62.

Maharsi RG, Sari KI, Wihardja R, Indrati I, Nur’aeny N. Efek perilaku mengunyah terhadap indeks massa tubuh. Padjadjaran Journal of Dental Researchers and Students. 2018;2(2):148–52.

Mazhar M, Zhu Y, Qin L. The interplay of dietary fibers and intestinal microbiota affects type 2 diabetes by generating short-chain fatty acids. Foods. 2023;12(1023):1–18.

Noviasari S, Kusnandar F, Setiyono A, Budijanto S. Beras analog sebagai pangan fungsional dengan indeks glikemik rendah. Jurnal Gizi dan Pangan. 2015;10(3):225–32.

Asif M. The prevention and control the type-2 diabetes by changing lifestyle and dietary pattern. Journal of Education and Health Promotion. 2014;3(1):1–8.

DOI: http://dx.doi.org/10.21927/ijnd.2024.12(4).284-295