The effectiveness of aromatherapy combination of pepperlav (peppermint and lavender) to relieve nausea vomiting in pregnant women

Isti Chana Zuliyati, Annisa Fatmawati, Sundari Mulyaningsih


Background : Nausea and vomiting in first trimester pregnant women can cause symptoms of prenatal distress and stress which will affect a mother’s quality of life. Nausea and vomiting will also affect the nutritional intake of the mother and fetus. Nutritional needs that are not fulfilled from the beginning of pregnancy can cause fetal growth restriction which can cause short and long term complications and have a negative impact on quality of life.

Objectives : This research aims to test the combination aromatherapy product Pepperlav (Peppermint and Lavender) in pregnant women to relieve nausea and vomiting.

Methods : This study pretest-posttest control group design method with a total sample of 40 first trimester pregnant women who experienced nausea and vomiting. This research was conducted at the Midwife Independent Practice in the Bantul Region. Data collection was carried out by interviewing and filling out questionnaires that measured nausea and vomiting before and after the intervention. The questionnaire used is a valid and reliable RINVR. Intervention were carried out by administering Pepperlav Aromatherapy Combinations with formulations FIB (40:50:10), F2B (30:60:10), F3B (20:70:10) with VCO based notes that have fulfilled the physical stability, homogeneity, measurement PH, spreadability and adhesion tests, product safety tests and preference tests conducted on women who are not pregnant. Data were analyzed using the Paired t Test.

Results : Based on statistical tests with Paired t test analysis p value: 0.001, this shows that the p value <0.05, there is a significant effect on the administration of pepperlav aromatherapy in Formula 1 formulation (a combination of 40% peppermint, 50% Lavender and 10% VCO.

Conclusions : Aromatherapy combination of Pepperlav (peppermint and lavender) can relieve nausea and vomiting in pregnant women.


nausea and vomiting; aromatherapy; peppermint; lavender

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Mccarthy FP, Khashan AS, North RA, Moss-morris R, Baker PN, Dekker G, et al. A Prospective Cohort Study Investigating Associations between Hyperemesis Gravidarum and Cognitive , Behavioural and Emotional Well-Being in Pregnancy. PLos One. 2011;6(11):1–7.

Liu M-C, Kuo S-H, Chou F-H, Chan T-F, Yang Y-H. Transformation of quality of life in prenatal women with nausea and vomiting. Women and Birth : Journal of the Australian College of Midwifes. 2019 Dec;32(6):543–8.

Chew LC, Verma RP. Fetal Growth Restriction. In Treasure Island (FL); StatPearls Publishing; 2022.

Widiasari NPA, Trapika IGMSC. Pola Pemberian Terapi Mual dan Muntah pada Ibu Hamil oleh Doktter Spesialis Obstetri dan Ginekologi serta Bidan di Kota Denpasar. E-Jurnal Medika [Internet]. 2017;6(5):28–35. Available from:

Wegrzyniak LJ DO, John T.Repke M, Serdar H. Ural M. Treatment of hyperemesis gravidarum. Riviews in Obstetric & Gynecology. 2012; 5 (2):78–84.

Rosalinna R. Aromaterapi Lavender Terhadap Pengurangan Mual Muntah Pada Ibu Hamil. Jambura Health and Sport Journal. 2019;1(2):48–55.

Hongratanaworakit T, Soontornmanokul S, Wongareesanti P. Development of aroma massage oil for relieving muscle pain and satisfaction evaluation in humans. Journal of Applied Pharmaceutical Science. 2018;8(4):126–30.

Hunt R, Dienemann J, Norton HJ, Hartley W, Hudgens A, Stern T, et al. Aromatherapy as treatment for postoperative nausea: A randomized trial. Anesthesia and Analgesia. 2013;117(3):597–604.

Mahmoud R, Ghani A, Tawfik A, Ibrahim A. The Effect of Aromatherapy Inhalation on Nausea and Vomiting in Early Pregnancy : A Pilot Randomized Controlled Trial. Journal of Natural Sciences Research.2013;3(6):10–22.

Joulaeerad N, Ozgoli G, Hajimehdipoor H, Ghasemi E, Salehimoghaddam F. Effect of aromatherapy with peppermint oil on the severity of nausea and vomiting in pregnancy: A single-blind, randomized, placebo-controlled trial. Journal of Reproduction and Infertility. 2018;19(1):32–8.

Prasetya Toepak E, Retnowati R. Isolasi Dan Karakterisasi Terhadap Minyak Mint Dari Daun Mentha Arvensis Segar Hasil Distilasi Uap-Air. Kimia student Journal.2013;2(2):574–9.

Olapour A, Behaeen K, Akhondzadeh R, Soltani F, Razavi FAS, Bekhradi R. The effect of inhalation of aromatherapy blend containing lavender essential oil on cesarean postoperative pain. Anesthesiol Pain Med. 2013;3(1):203–7.

Fatmawati A. Formulasi Dan Evaluasi Sediaan Aromaterapi Blended Peppermint, Lavender Dan Lemon Sebagai Antiemetika. INPHARNMED Journal (Indonesian Pharmacy Natural Medicine Journal). 2022;5(2):8.

Notoadmodjo. Metodologi Penelitian Kesehatan.Jakarta : Rineka Cipta;2012

Weigel MM, Weigel RM. The association of reproductive history, demographic factors, and alcohol and tobacco consumption with the risk of developing nausea and vomiting in early pregnancy. American Journal of Epidemiology. 1988 Mar;127(3):562–70.

Davis M. Nausea and vomiting of pregnancy: an evidence-based review. The Journal Perinatal & Neonatal Nursing. 2004;18(4):312–28.

GZhang H, Wu S, Feng J, Liu Z. Risk factors of prolonged nausea and vomiting during pregnancy. Risk Manag Healthc Policy. 2020;13:2645–54.

Ermaya D, Patria A, Hidayat F, Razi F. Pengembangan Minyak Nilam Sebagai Aromaterapi Dan Potensinya Sebagai Produk Obat. Rona Tek Pertan. 2019;12(2):58–63.

Jayasekara C, Gunathilake K. Processing technologies for virgin coconut oil and coconut based Confectionaries and beverages. Proceedings of International … [Internet]. 2007;(August). Available from:

Shijna Kappally AS and AS. a Review of Potential Applications. Hygeia.J.D.Med. 2015;7(2):34–41.

Ana S. Trimester Pertama Kehamilan Anda : Fase-Fase Paling Mendebarkan. Yogyakarta: Buku Biru; 2010.



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