Effect of Physical Exercise on Fatigue in Cervical Cancer Patients

Fatwa Imelda, Nur Afi Darti, Farida Linda Sari Siregar


Cervical cancer is the first female health problem in Indonesia with a high mortality rate. Fatigue is a common problem in patients with cervical cancer, fatigue due to cancer is different from fatigue of normal people. One of the self-empowerment recommended for managing post-therapy fatigue is physical exercise. Objective: to examine the effect of physical exercise on fatigue in cervical cancer patients. Metods: a quasy-experimental research with pretest-posttest with control group design was used. Thirty-four respondents were selected using purposive sampling in this study, which 17 respondents were randomly assigned in the experiment and control group. The Piper Fatigue Scale (PFS) was used to measure fatigue level. Paired t-test and Independent t-test were used for data analysis. Results: there was a significant effect of physical exercise on the decrease of fatigue levels in cervical cancer patients with p-value 0.000 (p<0.05), t= -5.794. Conclusion: physical exercise can be recommended in reducing fatigue levels in patients with cervical cancer.


Cervical cancer; physical exercise; fatigue

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Young-McCaughan S, Arzola SM. Exercise Intervention Research for Patients With Cancer on Treatment. Semin Oncol Nurs. 2007;

Wang XS, Zhao FM, Fisch MJ, O’Mara AM, Cella D, Mendoza TR, et al. Prevalence and Characteristics of Moderate To Severe Fatigue. Cancer. 2014;

Schmitz JM, Green CE, Hasan KM, Vincent J, Suchting R, Weaver MF, et al. PPAR-gamma agonist pioglitazone modifies craving intensity and brain white matter integrity in patients with primary cocaine use disorder: a double-blind randomized controlled pilot trial. Addiction. 2017;

Labourey JL. Physical activity in the management of cancer-related fatigue induced by oncological treatments. Ann Readapt Med Phys. 2007;

Katz AJ, Santoro M, DiBlasio F, Ashley R. Stereotactic Body Radiation Therapy for Low, Intermediate, and High-risk Prostate Cancer: Disease Control and Quality of Life. Int J Radiat Oncol. 2011;

Jones LW, Eves ND, Haykowsky M, Freedland SJ, Mackey JR. Exercise intolerance in cancer and the role of exercise therapy to reverse dysfunction. The Lancet Oncology. 2009.

Green E, Dudgeon D, Urowitz S, Molloy S, Pereira J, Mahase W, et al. Population-Based Standardized Symptom Screening: Cancer Care Ontario’s Edmonton Symptom Assessment System and Performance Status Initiatives. J Oncol Pract. 2014;

Bower JE, Greendale G, Crosswell AD, Garet D, Sternlieb B, Ganz PA, et al. Yoga reduces inflammatory signaling in fatigued breast cancer survivors: A randomized controlled trial. Psychoneuroendocrinology. 2014;

Barsevick AM, Cleeland CS, Manning DC, O’Mara AM, Reeve BB, Scott JA, et al. ASCPRO Recommendations for the Assessment of Fatigue as an Outcome in Clinical Trials. J Pain Symptom Manage. 2010;

RI. KK. Buku Panduan Pelaksanaan IVA-Sadari. Jakarta: Bakti Husada; 2015.

Meneses-Echávez, J. F., González-Jiménez, E., &Ramírez-Vélez R. Effects of supervised exercise on cancer-related fatigue in breast cancer survivors: a systematic review and meta-analysis. BMC Cancer. 2015;15(77):1–13.

Liu, L., Rissling, M., Neikruga, A., Fiorentino, L., Natarajan, L., Faiermana, M., Ancoli-Israel S. Fatigue and Circadian Activity Rhythms in Breast Cancer Patients Before and After Chemotherapy: A Controlled Study. PMC. 2013;1(1–2):12–26.

Atkinson, T. M., Li, Y., Coffey, C. W., Sit, L., Shaw., M., Lavene, D., Basch E. Reliability of adverse symptom event reporting by clinicians. Qual Life Res. 2012; 21:1159–1164.

Wahyuni, I.S., Sudiana, I. K., Mariyanti H. Walking Exercise Programme (WEP)Menurunkan Cancer Related Fatigue (CRF) pada Pasien Kanker Payudara di RSUD. Surabaya: Ibnu Sina Gresik, Fakultas Keperawatan. Universitas Airlangga; 2012.

Vitkauskaitė, E., Juozaitytė, E., Druktenienė, J., Bunevičius R. A systematic review of cancer related fatigue. Biol Psichiatr Ir Psicho Farmakol. 2011;13(2):74–7.

Cahyati P. Skripsi Pengaruh Relaksasi Otot Progresif Terhadap Penurunan Skor Fatigue Pada Pasien Kanker Payudara Yang Menjalani Kemoterapi di Rumah Sakit Kota Padang Tahun 2017.

Taukhid M. Manajemen Fatigue Melalui Kombinasi Aerobik dengan Relaksasi Yoga pada Penderita Kanker Payu dara dalam Program Kemoterapi. J Ilmu Kesehat. 2017;5(2):29–37.

Sulistini, R., Yetti, K., Hariyati TS. Faktor-Faktor yang Mempengaruhi Fatigue pada Pasien yang Menjalani Hemodialisis. J Keperawatan Indones. 2012; 15 (2):75–82.

Mollaoglu M. Fatigue in People Undergoing Haemodialysis: Clinical Perspective. Dyalisis Transplant. 2009; 38 (6):1–5.

Wiharja A. The New Perspective of Exercise as a Breast Cancer Therapy. J Med Heal. 2016;1(3):287–95.

Irianti, E., Ardinata D. Pengaruh Aktivitas Fisik Sedang Terhadap Hitung Lekosit dan Hitung Jenis Lekosit pada Orang Tidak Terlatih. Universitas Sumatera Utara; 2008.

Lucía, A., Earnest, C., Pérez M. Cancer-related fatigue: can exercise physiology assist oncologists?. Lancet Oncol. 2013; 4: 616–625.

Greenberg J. Psychoanalytic Goals, Therapeutic Action, And The Analyst’s Tension. Psychoanal Quarterly, LXXI. 2002; 651–78.

DOI: http://dx.doi.org/10.21927/jnki.2019.7(1).41-46


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