12.png)
Email this article Relationship between vitamin D, vitamin C and blood glucose in patients with type 2 diabetes mellitus
Abstract
ABSTRAK
Latar Belakang: Diabetes Melitus merupakan penyakit kronis yang terjadi ketika pankreas tidak lagi cukup dalam memproduksi insulin. Diabetes Melitus sebagai salah satu dari lima penyakit tidak menular yang menyebabkan kematian tertinggi sehingga diprioritaskan untuk pencegahan dan pengendaliannya. Beberapa penelitian vitamin D dan vitamin C menunjukkan kecendrungan variasi pro dan kontra dalam peningkatan sensitivitas insulin penderita Diabetes Melitus.
Tujuan: mengetahui hubungan konsumsi vitamin D dan vitamin C dengan kadar glukosa darah pada pasien rawat jalan Diabetes Melitus tipe 2 Rumah Sakit Umum Daerah Harapan dan Doa Kota Bengkulu.
Metode: Desain penelitian observasional analitik dengan pendekatan cross sectional. Populasi penelitian adalah pasien diabetes melitus tipe 2. Sampel sebanyak 57 pasien dengan teknik purposive sampling. Analisis data menggunakan uji Korelasi.
Hasil: Uji korelasi vitamin D dengan glukosa darah menunjukkan nilai p = 0,238, sedangkan vitamin C dengan kadar glukosa darah adalah nilai p = 0,000.
Kesimpulan: Tidak ada hubungan konsumsi vitamin D dengan kadar glukosa darah, namun ada hubungan konsumsi vitamin C dengan kadar glukosa darah pada pasien rawat jalan Diabetes Melitus tipe 2.
KATA KUNCI: Vitamin D; Vitamin C; glukosa darah; Diabetes melitus tipe 2
ABSTRACT
Background: Diabetes mellitus is a chronic disease that occurs when the pancreas no longer produces enough insulin. Diabetes mellitus is one of the five non-communicable diseases with the highest mortality rate, therefore, its prevention and control are prioritized. Several studies on vitamin D and vitamin C have shown varying trends in improving insulin sensitivity in people with diabetes mellitus.
Objectives: To determine the relationship between vitamin D and vitamin C consumption and blood glucose levels in outpatients with type 2 diabetes mellitus at Harapan dan Doa Regional General Hospital, Bengkulu City.
Methods: The study design was an observational analytical study with a cross-sectional approach. The study population was patients with type 2 diabetes mellitus. A sample of 57 patients was selected using a purposive sampling technique. Data analysis used a correlation test.
Results: The correlation test for vitamin D and blood glucose showed a p-value of 0.238, while the correlation between vitamin C and blood glucose levels showed a p-value of 0.000.
Conclusions: There is no relationship between vitamin D consumption and blood glucose levels, but there is a relationship between vitamin C consumption and blood glucose levels in outpatients with type 2 diabetes mellitus.
KEYWORDS: Vitamin D; Vitamin C; blood glucose; type 2 diabetes mellitus
Keywords
Full Text:
PDFReferences
World Health Organization. 2024. Available from: https://www.who.int/news-room/fact-sheets/detail/diabetes
Webber S. International Diabetes Federation [Internet]. 10 th. Vol. 102, Diabetes Research and Clinical Practice. 2021. 147–148 p. Available from: www.diabetesatlas.org
Kemenkes R. Peraturan Menteri Kesehatan Republik Indonesia. In 2019; 2019. p. 5–10. Available from: https://peraturan.bpk.go.id/Details/138621/permenkes-no-28-tahun-2019
Sarifah M, Siyam N. Determinan Diabetes Melitus Tipe II di Posbindu PTM Puskesmas Pegandon Puskesmas Pegandon Kabupaten Kendal Tengah. 2023;7(3):365–75.
Gendy HI El, Sadik NA, Helmy MY, Rashed LA. Vitamin D receptor gene polymorphisms and 25(OH) vitamin D: Lack of association to glycemic control and metabolic parameters in type 2 diabetic Egyptian patients. J Clin Transl Endocrinol [Internet]. 2019;15(September 2018):25–9. Available from: https://doi.org/10.1016/j.jcte.2018.11.005
Nimse SB, Pal D. Free radicals, natural antioxidants, and their reaction mechanisms. RSC Adv. 2015;5(35):27986–8006.
Santosh HN, David CM. Role of ascorbic acid in diabetes mellitus: A comprehensive review. J Med Radiol Pathol Surg. 2017;4(1):1–3.
Purwaningtyastuti R, Nurwanti E, Huda N. Asupan vitamin C berhubungan dengan kadar glukosa darah pada pasien rawat jalan DM tipe 2. J Gizi dan Diet Indones (Indonesian J Nutr Diet. 2018;5(1):44.
Sirajuddin, Surmita TA. Survei Konsumsi Pangan. 2018th ed. Suhardianto Anang, editor. 2018; 2018. 381 p.
Wardani IS, Aliza Raudatin Sahly, Indana Eva Ajmala, Dewi Suryani. Vitamin D and Type 2 Diabetes Mellitus: Role in Insulin Resistance, Glycemic Control and Long Term Complications. Unram Med J. 2022;11(2):942–52.
Safnowandi S. Pemanfaatan Vitamin C Alami sebagai Antioksidan pada Tubuh Manusia. Biocaster J Kaji Biol. 2022;2(1):6–13.
Zakiyah FF, Indrawati V, Sulandjari S, Pratama SA. Asupan karbohidrat, serat, dan vitamin D dengan kadar glukosa darah pada pasien rawat inap diabetes mellitus. J Gizi Klin Indones. 2023;20(1):21.
Rochmah N, Probosari E, Dieny FF. Hubungan Asupan Vitamin D Dan Kalsium Dengan Kadar Glukosa Darah Puasa Wanita Obesitas Usia 45-55 Tahun. J Nutr Coll. 2017;6(4):285.
Utami BS, Bintanah S, Isworo JT. Hubungan Konsumsi Bahan Makanan Sumber Vitamin C dan Vitamin E dengan Kadar Gula Darah Penderita Diabetes Mellitus Tipe 2 Rawat Jalan di Rumah Sakit Tugurejo Semarang. J Gizi. 2015;4(1):18–23.
Wahidmurni. Peran Vitamin C, Vitamin E, Dan Tumbuhan Sebagai Antioksidan Untuk Mengurangi Penyakit Diabetes Mellitus. 2017;8(Iddm):2588–93.
Kordestani.S, et.al. Effect of Vitamin C Therapy on Serum Parameters in Patients with Type 2 Diabetes Mellitus: Clinical Trial. Iranian journal of diabetes and obesity. [Internet]. 2023.Availabe from:https://www.researchgate.net/publication/369219333_Effect_of_Vitamin_C_Therapy_on_Serum_Parameters_in_Patients_with_Type_2_Diabetes_Mellitus_Clinical_Trial
DOI: http://dx.doi.org/10.21927/ijnd.2025.13(5).%25p
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Indonesian Journal of Nutrition and Dietetics (IJND) indexed by:
View My Stats